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The company has established the enterprise goal of "survival by quality, reputation by quality, and development by quality. Strengthen the training of technical personnel, and constantly enrich the first-line technical force to ensure the normal operation of the quality assurance system.
Cleaning method of high shear emulsifying machine
Release time:
2022-05-05
The high-shear emulsifying machine is often used in the pharmaceutical compounding tank. It is a multifunctional compounding system and plays an important role in the mixing and stirring unit of pharmaceutical production. In the process of drug production, it is very important to remove the cross contamination of active ingredients, foreign matter and insoluble particles, and to reduce or eliminate the contamination of injection by microorganisms and pyrogens. What is the cleaning method of the material system combined with high-shear emulsifying machine and other equipment? Let's learn together!
High shear emulsifying machineCommonly used in pharmaceutical ingredient tanks, it is a multifunctional ingredient system that plays an important role in the mixing and stirring unit of pharmaceutical production. In the process of drug production, it is very important to remove the cross contamination of active ingredients, foreign matter and insoluble particles, and to reduce or eliminate the contamination of injection by microorganisms and pyrogens. What is the cleaning method of the material system combined with high-shear emulsifying machine and other equipment? Let's learn together!
The traditional sand mill can only grind two specific materials in use, and theoretically has emulsification effect, but the emulsification effect is not complete, and the fineness of the raw material mixture is not completely standard, which brings certain obstacles to the development of the material processing industry. In use, the sander can only grind solid and powder materials, and it is still limited in material processing and manufacturing. High shear emulsifiers can emulsify solid-solid, gas-solid.
Rotating the outer end of the rotor with a high shear emulsifier can produce a linear speed of more than 15 m/s, and at high times it can reach 40 m/s. It will also form friction and collision tearing between the mechanical layer and the liquid layer, effectively making the material fully dispersed, emulsified, homogenized, and crushed, and then sprayed through the slot of the stator. After continuous spraying, the material changes the overall flow direction under the resistance of the container wall. After several times, the material is ejected.
High shear emulsifying machinevarious processing flows;
Dispersion or mixing: used for syrup, shampoo, washing liquid, concentrated juice, yogurt, dessert, mixed dairy products, ink, enamel, pre-mixing, condiment production, stabilizer dissolution, smoke, salt, alumina, etc.
High shear emulsifying machine emulsifying process: used for drug emulsion, ointment, cream, mask, cream, emulsifying essence, oil-water emulsification, emulsified asphalt, resin emulsification, wax emulsification, waterborne polyurethane emulsification, pesticides, etc.
High shear emulsifying machineIt is the rapid and uniform distribution of one or more phases into another continuous phase, but under normal circumstances, the phases are immiscible. Due to the high tangential velocity generated by the high-speed rotation of the rotor and the strong kinetic energy generated by the high-frequency mechanical action, the material is subjected to strong mechanical and hydraulic shearing, centrifugal extrusion, liquid layer friction, impact tearing and turbulence in the narrow gap between the stator and the rotor. Comprehensive effect. Under the joint action of the corresponding mature technology and suitable additives, the liquid phase and the gas phase are dispersed and emulsified evenly, and the stable product is obtained through high-frequency circulation.
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