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How to do well the sample work of vacuum homogenization emulsifying machine


Release time:

2019-05-17

The small test and the pilot test of the vacuum homogenization emulsifier are to complete different tasks in different periods of time. The distinction between the two lies not only in the amount of feeding and the size of the equipment used. The small-scale test is mainly engaged in exploration and development work. The chemical small-scale test solves the reaction, separation process and analysis and identification of the materials involved. Qualified samples are taken out, and the economic and technical indicators such as yield meet the expected requirements, then it can be transferred to the pilot stage. The problem to be solved in the pilot test process is how to use industrial means and equipment to complete the whole process of the pilot test and basically achieve the economic and technical indicators of the pilot test. There is no lack of innovation and invention in the pilot process.

The small test and the pilot test of the vacuum homogenization emulsifier are to complete different tasks in different periods of time. The distinction between the two lies not only in the amount of feeding and the size of the equipment used.
The small-scale test is mainly engaged in exploration and development work. The chemical small-scale test solves the reaction, separation process and analysis and identification of the materials involved. Qualified samples are taken out, and the economic and technical indicators such as yield meet the expected requirements, then it can be transferred to the pilot stage.
The problem to be solved in the pilot test process is how to use industrial means and equipment to complete the whole process of the pilot test and basically achieve the economic and technical indicators of the pilot test. There is no lack of innovation and invention in the pilot process. In the small test, it is very simple to quantitatively move a material from one container to another vessel, but in the pilot test, it is necessary to solve the selection of what type, what specification, what material of the pump, what measurement method, and A series of issues such as safety, environmental protection, and corrosion protection. The pilot test is to solve the problems encountered in the process of using industrial devices and means, not only to ensure the material balance that is very important in the pilot test, but also to include the balance of heat and momentum that is not very important in the pilot test. To further expand the scale, to achieve the real industrial significance of the economic scale of mass production to provide a reliable process means and data base.
Vacuum homogenization emulsifying machine pilot scale-up experience summary:
The intermediate experimental stage of vacuum emulsifying machine is to further study the change law of chemical reaction conditions in a certain scale device, and solve the problems that can not be solved or found in the laboratory. Although the nature of the chemical reaction will not change due to the different experimental production, the optimal reaction process conditions for each step of the chemical reaction may vary with the external conditions such as the experimental scale and equipment.
Vacuum homogenizing emulsifier experiment to what stage before the pilot test? At least the following conditions should be met:
The yield of small test is stable and the product quality is reliable.
The manufacturing conditions have been determined, and the analytical test methods for products, intermediates and principles have been determined.
Some equipment, pipe material corrosion resistance test has been carried out, and there are general equipment required.
A material balance was performed. There are preliminary treatment methods for the three wastes.
The specifications and unit consumption quantities of raw materials have been proposed.
Safety requirements have been put forward.
Vacuum homogenization emulsifying machine pilot scale-up methods are:
Experience amplification method: mainly by virtue of experience through step-by-step amplification (small test device-intermediate device-medium-sized device-large device) to explore the characteristics of the reactor. It is also the main method currently used in drug synthesis.
Similar amplification method: mainly applies the principle of similarity to enlarge. This method has some limitations and is only applicable to physical process amplification. It does not apply to the amplification of chemical processes.
Mathematical simulation amplification method: is the application of computer technology amplification method, it is the direction of future development.
In addition, the development of micro intermediate devices is also very rapid, that is, the use of micro intermediate devices instead of large intermediate devices, to provide accurate design data for industrial devices. Its advantages are low cost and fast construction.